Drug Interactions With Boceprevir

More Detail on Drug Interactions With Boceprevir

The following sections explain in detail the potentially negative interactions that can occur when boceprevir is combined with any of the drugs listed above.
 
Antiarrhythmic Medications
Boceprevir may increase blood levels of antiarrhythmic medications, potentially increasing your risk for serious side effects. Your healthcare provider will monitor you closely if you take these medications together.
 
Bosentan
Boceprevir can increase blood levels of bosentan, possibly increasing the risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Certain Alpha Blockers
Boceprevir can increase blood levels of certain alpha blockers, potentially causing dangerous side effects. Boceprevir should not be combined with these medications. 
 
Certain Antifungal Medications
Boceprevir may increase blood levels of certain antifungal medications, potentially increasing your risk for serious side effects. Your healthcare provider may need to give you lower antifungal doses if you take one of these medications with boceprevir.
 
Certain Antiseizure Medications
Carbamazepine, phenobarbital, and phenytoin can decrease boceprevir blood levels, potentially making the medication less effective. Talk to your healthcare provider if you take one of these antiseizure medications (also called antiepileptics). They should not be taken with boceprevir.
 
Certain Benzodiazepines
Boceprevir can increase blood levels of alprazolam, triazolam, and midazolam, potentially increasing your risk for side effects. You should not take triazolam or oral midazolam during boceprevir treatment. Talk to your healthcare provider before taking boceprevir with a benzodiazepine. Your healthcare provider can choose one that is not likely to interact with boceprevir, or adjust your benzodiazepine dosage if needed.

Boceprevir Medication Information

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