Engerix-B Drug Interactions

You may experience drug interactions with Engerix if you are taking an immunosuppressant or an anticoagulant medication. For example, if you are taking an immunosuppressant, your immune system may not be able to respond fully to Engerix, making the vaccine less effective. To reduce your risk of interactions, tell your healthcare provider about all of the medications you are taking.

An Overview of Interactions With Engerix-B

 Engerix-B® (hepatitis B vaccine) can potentially interact with a few medications. Some of the medicines that may lead to Engerix-B drug interactions include:
 
 
 
    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:
 
      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)
 
    • Cyclophosphamide (Cytoxan®)
    • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
    • Etanercept (Enbrel®)
    • Methotrexate (Rheumatrex®)
    • Mycophenolate (CellCept®)
    • Sirolimus (Rapamune®)
    • Tacrolimus (Prograf®).
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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