Epivir and Pregnancy

In studies on Epivir and pregnancy, the medication increased the risk of miscarriages when it was given to pregnant rabbits. Animals do not always respond to drugs the same way that humans do, however, so healthcare providers can prescribe the drug to pregnant women if the benefits outweigh the possible risks. If you are taking Epivir and pregnancy occurs, contact your healthcare provider immediately.

Epivir and Pregnancy: An Overview

Epivir® (lamivudine) is a prescription AIDS, HIV, and hepatitis B medication. It is not known whether Epivir is safe for use during pregnancy. However, in some circumstances, the benefits of Epivir may outweigh the potential risks.

Epivir and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating. While there have been no adequate studies of Epivir in pregnant woman, the drug has been studied in pregnant animals.
Epivir has been studied in pregnant rabbits and rats. Epivir did not appear to increase the risk of birth defects. In rabbits (but not in rats), Epivir seemed to increase the risk of miscarriages. However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to pregnant women if a healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child. In general, case reports of Epivir use in pregnant women suggest that it is probably safe for use in pregnancy, although the full risks are not currently known.
Pregnancy and Pain

Epivir for HBV

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