Epivir Drug Interactions

When zalcitabine, ribavirin, or interferon medications are taken together with Epivir, drug interactions may potentially occur. These interactions could increase the level of Epivir in your blood, decrease the effectiveness of the medicines, or increase your risk for dangerous side effects. Telling your healthcare provider about other drugs you are taking can help prevent these negative Epivir interactions.

 

Epivir Drug Interactions: An Introduction

Epivir® (lamivudine) can potentially interact with a few other medicines. Some of these medicines that may lead to Epivir interactions include:
 
  • Interferon medications, such as:

 

    • Interferon alfa-2a (Roferon®-A)
    • Interferon alfa-2b (Intron® A)
    • Interferon alfa-2b and ribavirin (Rebetron®)
    • Interferon alfa-n3 (Alferon® N)
    • Interferon alfacon-1 (Infergen®)
    • Interferon beta-1a (Avonex®, Rebif®)
    • Interferon beta-1b (Betaseron®)
    • Interferon gamma-1b (Actimmune®)
    • Peginterferon alfa-2a (Pegasys®)
    • Peginterferon alfa-2b (PEG-Intron®)

 

  • Ribavirin (Copegus®, Rebetol®, Ribasphere®, Virazole®)
  • Trimethaprim and sulfamethoxazole (Bactrim®, Septra®)
  • Zalcitabine (Hivid®).
     

Epivir Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Epivir is combined with any of the drugs listed above.
 
(Epivir Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;