Epivir Uses

Epivir for HIV and AIDS

AIDS is short for "Acquired Immune Deficiency Syndrome." AIDS was first reported in the United States in 1981. Since then, it has since become a significant worldwide epidemic. AIDS is caused by the human immunodeficiency virus (HIV). Initially, an HIV infection usually does not cause any obvious symptoms (see HIV Symptoms). However, by killing or damaging cells of the body's immune system, HIV will eventually begin to progressively destroy the body's ability to fight infections and certain cancers (see AIDS Symptoms).
 
HIV is often spread through sexual contact with an infected partner. HIV transmission also happens through contact with infected blood, which frequently occurs among IV drug users (who share needles or syringes contaminated with blood from someone infected with the virus). Women with HIV can transmit the virus to their babies during pregnancy, birth, or breastfeeding.
 
Epivir is not a cure for HIV or AIDS. In fact, there is currently no known cure for HIV or AIDS. Also, Epivir is not intended to be used alone. Instead, it is used as part of an HIV "cocktail." These cocktails usually consist of three or four (sometimes even five) different HIV medications (technically known as highly active antiretroviral therapy or HAART). Using combinations of medications helps to prevent the virus from becoming resistant to one or more of the drugs.
 

How Does Epivir Work?

Epivir belongs to group of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). NRTI medications work by blocking a process that the HIV and hepatitis B viruses need in order to multiply.
 
HIV (the human immunodeficiency virus) is the virus that is responsible for AIDS, and HBV (the hepatitis B virus) is responsible for hepatitis B infection. Like other viruses, HIV and HBV must use a person's own cells to reproduce. However, HIV and HBV are different from many other viruses because they must first convert their genetic material from RNA to DNA. It is the DNA genes that allow HIV and HBV to multiply.
 
HIV and HBV convert their genetic material into DNA by using a special protein called the reverse transcriptase enzyme. To create DNA, this enzyme uses several different protein building blocks.
 
Epivir works by tricking reverse transcriptase into thinking it is one of these protein building blocks. However, it is just different enough that when used to create DNA, Epivir actually stops the DNA from being made. Without DNA, HIV and HBV cannot multiply. It is important to understand that Epivir is not a cure for HIV, AIDS, or hepatitis B.
 
(Epivir Uses Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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