Hepatitis B Vaccine

How Long Does the Hepatitis B Vaccine Protect You?

Recent studies show that after receiving the hepatitis B vaccine, you will be protected for at least 23 years.
Booster doses of hepatitis B vaccine are not recommended routinely for people who are not immune compromised. Data show that vaccine-induced anti-HBs levels might decline over time; however, immune memory remains intact indefinitely following immunization. Immune-competent people with declining antibody levels are still protected against clinical illness and chronic disease.

Side Effects

There are very few side effects from the hepatitis B vaccine. The most common side effects are soreness where you got the shot and fatigue.
You will not get hepatitis B from the vaccine.
(See Engerix-B Side Effects or Recombivax HB Side Effects for more information.)

Combination Hepatitis A and B Vaccine

Twinrix® is a vaccine for both hepatitis A and hepatitis B. It combines two FDA-approved vaccines -- Havrix®, for hepatitis A; and Engerix-B®, for hepatitis B. It protects individuals 18 years of age or older against diseases caused by hepatitis A and hepatitis B viruses.
The vaccine is recommended for travelers whose occupation or behavior puts them at high risk of exposure to the hepatitis B virus, or who are visiting countries with a high or intermediate rate of both hepatitis viruses, as defined by the Centers for Disease Control and Prevention.

Hepatitis B Immunoglobulin

If you know you were recently exposed to the hepatitis B virus, you may get protection from a shot of hepatitis B immunoglobulin (HBIG) within 24 hours after your exposure. This will protect you for three to six months, but it is also strongly recommended that you begin the three-shot hepatitis B vaccine series within seven days of your exposure.
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What Is Hepatitis B?

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