Drug Interactions With Peginterferon Alfa-2a

Methadone
Peginterferon alfa-2a may increase the level of methadone in the blood, perhaps increasing the risk for side effects. Check with your healthcare provider before using these medications together.
 
Pegloticase
Pegloticase can make peginterferon alfa-2a less effective. Check with your healthcare provider before using these medications together.
 
Telbivudine
Interferons, including peginterferon alfa-2a, may increase the risk for telbivudine side effects. In general, telbivudine should not be combined with interferon medications.
 
Theophylline (Elizophyllin, Theo-24, TheoCap, Theochron, Uniphyl)
Interferons, including peginterferon alfa-2a, may increase the level of theophylline in your blood, increasing the risk for side effects. Your healthcare provider may need to monitor your theophylline blood levels and adjust your dosage as necessary.
 
Zidovudine (Retrovir, Combivir, Trizivir)
Peginterferon alfa-2a may increase the level of zidovudine in your blood, increasing your risk for potentially serious side effects. Talk with your healthcare provider before using these medications together.
 

Final Thoughts

Many drugs may interact with peginterferon alfa-2a, including some that were not discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.

Peginterferon Alfa-2a Information

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