Peginterferon Alfa-2a Dosage

Peginterferon Alfa-2a Dosing Guidelines for Hepatitis B

The recommended peginterferon alfa-2a dose for treating hepatitis B in adults is 180 mcg each week for 48 weeks. This medicine is not approved for treating hepatitis B in children.

General Information on Using Peginterferon Alfa-2a

Some considerations to keep in mind during treatment with peginterferon alfa-2a include the following:
  • Peginterferon alfa-2a comes as an injection that is given just under the skin (subcutaneously) once a week for 24 to 48 weeks.
  • Use peginterferon alfa-2a on the same day each week.
  • This medication comes in a vial, a prefilled syringe, or an autoinjector. All forms are for a single use only. Any unused portion must be discarded; it cannot be saved for later.
  • It is best to inject peginterferon alfa-2a into areas of the skin that have a layer of fat underneath. This includes the thigh or abdomen (stomach), away from the navel (belly button). Try to rotate the injection sites; do not inject in the same place twice in a row.
  • Never shake peginterferon alfa-2a, as this could damage the delicate medication. Make sure to take the medication out of the fridge for 20 minutes before administering the dose to allow it to come to room temperature.
  • Make sure your healthcare provider teaches you exactly how to inject peginterferon alfa-2a. This includes:
    • How to prepare the skin
    • How to prepare and mix the injection
    • How to inject the medication
    • What to do with your used needles (this may vary, depending on the local laws and regulations).
If you are not comfortable with any part of the process, please let your healthcare provider know.
  • For the medication to work properly, it must be used as prescribed. Peginterferon alfa-2a will not work if you stop using it too soon.
  • If you are unsure about anything related to your dosage or peginterferon alfa-2a dosing in general, please talk with your healthcare provider or pharmacist.

Peginterferon Alfa-2a Information

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