Drug Interactions With Telaprevir

More Detail on Drug Interactions With Telaprevir

The following sections explain in detail the potentially negative reactions that can occur when telaprevir is combined with any of the drugs listed above.
 
Alfuzosin
Telaprevir and alfuzosin should never be combined, due to the risk of dangerously low blood pressure (hypotension) or an irregular heart rhythm (arrhythmia).
  
Arrhythmia Medications
Telaprevir may increase blood levels of antiarrhythmic medications, potentially increasing your risk for serious side effects. Your healthcare provider will monitor you closely if you take these medications together.
 
Bosentan
Telaprevir can increase blood levels of bosentan, possibly increasing the risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medications together.
 
Calcium Channel Blockers
Telaprevir may increase blood levels of calcium channel blockers, possibly increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medicines together, and adjust your calcium blocker dosage if needed.
 
Certain Antibiotics
When telaprevir is taken with certain antibiotics, it can increase the blood levels of the antibiotics and telaprevir. Your healthcare provider will closely monitor you for potential side effects if you take these medications together.
 
Certain Antifungal Medications
Telaprevir may increase blood levels of certain antifungal medications, potentially increasing your risk for serious side effects. In addition, the antifungals listed above can increase blood levels of telaprevir. High ketoconazole and itraconazole doses should not be given to people who are taking telaprevir. Because of unpredictable effects on voriconazole blood levels, it should not be used at all in people taking telaprevir, unless absolutely necessary.

Telaprevir Medication Information

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