Drug Interactions With Telaprevir

Digoxin
Telaprevir may increase levels of digoxin in the bloodstream. Your healthcare provider may decide to monitor your digoxin levels using a simple blood test, especially when you first start or stop taking telaprevir.
 
Desipramine
Taking telaprevir with desipramine could increase the level of desipramine in your bloodstream, potentially increasing your risk for side effects, such as nausea, dizziness, and low blood pressure. Your healthcare provider may need to give you a lower desipramine dose during telaprevir treatment.
 
Ergot Medications
Telaprevir increases the risk of dangerous ergot side effects. Such medications should never be combined.
  
Escitalopram
Telaprevir can decrease blood levels of escitalopram, potentially making it less effective. Although this is not considered a serious interaction, your healthcare provider may choose to monitor you more closely during telaprevir treatment and increase your escitalopram dose if needed.
 
Fentanyl or Alfentanil
Telaprevir may increase blood levels of fentanyl or alfentanil. Check with your healthcare provider before taking such medications together. Extra monitoring may be required to avoid dangerous side effects.
 
Hormonal Birth Control
Telaprevir has been shown to decrease blood levels of ethinyl estradiol, which could make birth control pills that contain estrogen less effective. Women taking telaprevir should use two forms of birth control, other than hormonal birth control.
 
Methadone
Taking telaprevir with methadone could decrease levels of methadone in your bloodstream, potentially making it less effective. Your healthcare provider may choose to monitor your response to methadone, and adjust your dose if needed.

Telaprevir Medication Information

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