Telaprevir for Non-Responders
By preventing the hepatitis C virus from multiplying, telaprevir (INCIVEK®) can help treat genotype 1 chronic hepatitis C in adults. Specifically, telaprevir is approved for use in non-responders, meaning people who have failed previous treatment. Also, this drug is used in people with stable liver problems who have not been previously treated.
Telaprevir works to treat hepatitis C infections by blocking the activity of enzymes called proteases. Protease enzymes are used by the hepatitis C virus to multiply. By blocking the protease enzyme, telaprevir prevents the hepatitis C virus from reproducing.
Telaprevir should not be used alone. It is only approved for use in combination with peginterferon alfa (Pegasys®, PEG-Intron®) and ribavirin (Copegus®, Rebetol®, RibaPak®, Ribasphere®).
(Click What Is Telaprevir Used For? for an in-depth look at how telaprevir can prevent the hepatitis C virus from spreading and who it is specifically approved for. This article also describes the results of clinical studies on the drug's effectiveness and why it may not be safe for children and older adults.